Monday, May 4, 2009

Why is a sexual reproduction important for a medical research?

how could it help or why is it so important for medical or biological researches?

Why is a sexual reproduction important for a medical research?
Most of the experiments they do requires living organisms, and they cannot mafacture that. If they increase the sexual reproduction, they get more products and better results, with a higher amount of diversity.
Reply:In genetic experiments using mouse models or rat models, you have to introduce the mutated gene of interest into the organism. To do that, you do what is called cell transformation. In essence, you insert your gene of choice into an embryonic stem cell (or rather, a whole batch of them). It's as simple as putting the two together in a solution and then shocking the cell with electricity.





Once you've got a transformed cell expressing your gene of choice, you then insert it into a blastocyst. Implant that into a rat or mouse, then let it grow into a mice pups.





Of course, these new mice or rats won't express the gene fully. Why? Well, when you insert your transformed embryonic stem cells into the blastocyst, you need a few stem cells inside to begin with to make up the numbers. So your mouse will only express half of the desired genes if lucky.





You then cross-breed and select for the ones that fully express the genes in all cells.


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