The question is vague. No one signs up at a medical research center to be a guinea pig for any and all "experiments" that might be done on humans. It doesn't work that way.
If anyone wants to do human research, like on a newly invented medicine or a new treatment for one type of cancer, there is a legal set of procedures that must first be followed, included writing up the details of the plan, justification, review by an institutional research review board (consisting of different professionals like doctors, lawyers, ministers, lay people, ethicist), development of a simple and legal consent form for volunteers or patients, and then recruitment of screened applicants. You might then sign up for a specific experiment if you are an acceptable candidate.
Signing up is voluntary, and anyone who signs up is allowed to quit anytime they wish along the way. Such volunteers are invaluable and the only way to get approval of any advances in medicine.
I have been a human volunteer to test a new vaccine. I have worked with volunteers both in this country and overseas to test new medicines against malaria and other diseases. Yes, there is some personal risk, but the possibiulities of helping many others is a great high and need throughout the world.
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